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 Carsil (Silymarin)
 Carsil (Silymarin)Introduction
 Carsil (Silymarin) a result of natural product
 Carsil mechanism of action
 Carsil pharmacological studies
 Carsil pharmacokinetic studies
 Tolerance to Carsil, toxicological studies
 Clinical use of Carsil
 Carsil in chronic liver disease (CLD)
 Carsil indications
 Carsil adverse reactions, contraindications, Administration and posology, Storage
 Table of contents
Carsil package insert
 Silymarin substance
 Carsil 80 tabl x 35 mg
Carsil (Silymarin) is a product of plant origin with hepatoprotective and antioxidative action. The active component of Carsil is Silymarin derived from Silibum Marianum (Milk Thistle, Bulgarian White Thorn). Silymarin, as the plant active ingredient of Carsil, has a consolidating effect on the cell membrane, thus protecting the liver from harmful impacts and facilitating the recovery of the impaired liver cells.
 
 
 
 
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  carsil (silymarin) home / 







Carsil Mechanism of Action   
 

MECHANISM OF ACTION

The anti-hepatotoxic effect of Silymarin is associated with the competitive interaction with the receptors of the relevant toxins in the hepatocyte membrane, and with a more general action of protective nature (Vogel 1975).

So, the hepatoprotective action of Carsil® (with Silymarin as generic name) is manifested by a consolidation of the membranes and the functions of the cell structures. Thus, a specific protective and curative effect on the liver protective function in this way.

The biflavonoids are assumed to possess a vitamin-C-sparing effect. They have an anti-inflammatory action and improve the synthesis of proteins and glycoproteins, as well as the peroxidation of lipids in the liver. Clinically, the above effects are translated into improved signs and symptoms, and lowered values of the transaminases, g-globulines and blood bilirubin.

 
 
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