TABLE OF CONTENTS

• Introduction to Carsil, Silymarin
  
• Carsil, Silymarin - a result of a natural product
  
• Mechanism of action of Silymarin
  
• Pharmacological studies of Carsil, Silymarin
  
  1. Intoxication with tetrachlormethane
     
  2. Intoxication with praseodymium nitrate
     
  3. Intoxication with ethanol
     
  4. Intoxication with phalloidin
     
  5. Intoxication with d-galactosamine
     
• Pharmacokinetic studies of Carsil, Silymarin
  
• Tolerance to Carsil, Silymarin. Toxicological studies of Silymarin
  
  • Acute toxicity
  • Subacute and chronic toxicity
    
  • Teratological studies
    
  • Mutagenicity studies
    
• Clinical use of Carsil, Silymarin
  
• Carsil, Silymarin in chronic liver diseases (CLD)
  
• Indications of Carsil, Silymarin
  
• Position of Carsil, Silymarin in the comprehensive therapy of:
  • Liver cirrhosis
    
  • Acute and chronic hepatitis
    
  • Toxometabolic liver damage
• Adverse reactions of Silymarin
  
• Contraindications of Silymarin
  
• Administration and posology Silymarin
  
• Storage of Silymarin

• Package Insert of Carsil, Silymarin